Header
Embedded Research Areas
These embedded research programs provide a platform for developing new bio-imaging technologies and for the integration of highly diverse data sets:
Microverse Imaging Center
Life science and optics experts work together to develop real-time imaging technologies at molecular resolution.
Data Synopsis
Experts develop new data mining approaches that are required for the large amounts of highly diverse data generated in the Microverse Cluster.
Microverse Imaging Center
We establish the Microverse Imaging Center that provides and advances state-of-the-art biomedical imaging technologies at high spatio-temporal resolution. On top of hosting state-of-the-art turnkey microscopes, the imaging facility also supports technological development and exchange between optics and life science expertes for shaping the imaging techniques of tomorrow.
At biosafety level 2, the facility currently offers two fluorescence microscopes:
The confocal laser scanning microscope LSM 980 with AiryScan 2 detector meets the needs for standard confocal applications including questions demanding an especially high sensitivity.
The multimodal camera-based system ELYRA 7 covers the high-speed and high-resolution applications, for instance using structured illumination microscopy.
Management Board:
Michael Bauer | Christian Eggeling | Marc Thilo Figge | Rainer Heintzmann | Aurélie Jost | Jürgen Popp | Ulrich Schubert | Andreas Tünnermann
For access to the microscopes, please contact the Head of Microverse Imaging Center Dr. Aurélie Jost or Microscope Manager Dr. Patrick Then.
More information can be found on the intranet.
Gnotobiotic Mouse Facility
The mammalian intestinal microbiota consists of various microorganisms which shape the host physiology and immunology. The complexity of microbiota composition and interaction between its members and the host impede the determination of mechanisms and consequence of distinct interactions. One solution to this problem is gnotobiology, the use of animals with a defined microbiological state.
Together with the Leibniz HKI we have established a gnotobiotic mouse facility at the Department of Microbial Immunology headed by Prof. Ilse Jacobsen.
Contact for the gnotobiotic facility: Dr. Alessia Montesano (alessia.montesano@leibniz-hki.de)
We are aware that animal testing comes with great responsibilty. Therefore we provide the best care for our mice. Moreover, Microverse scientists are developing and working with alternatives, such as organ-on-chip models.
More information on animal testing:
Data Synopsis
Building on our expertise in informatics and bioinformatics, we develop new data mining approaches that are required for the large amounts of highly diverse data generated in the Microverse Cluster. Only through the comprehensive mining and integration of data we will be able to identify cause-effect relationships and fundamental principles of microbial balance in different consortia and habitats.
Coordinators:
Marc Thilo Figge | Birgitta König-Ries