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Selected Publications

Selected publications from the Microverse investigators.

2024

Weigel A, Jacob P, Schweinberger W, Huber M, Trubetskov M, Karandušovský P, Hofer C, Buberl T, Amotchkina T, Högner M, Hahner D, Sulzer P, Leitenstorfer A, Pervak V, Krausz F, and Ioachim Pupeza (2024) Dual-oscillator infrared electro-optic sampling with attosecond precision.
Optica

Seibold P, Dörner S, Fricke J, Schäfer T, Beemelsmanns C, Hoffmeister D (2024) Genetic regulation of L-tryptophan metabolism in Psilocybe mexicana supports psilocybin biosynthesis. Fungal Biology and Biotechnology. doi: 10.1186/s40694-024-00173-6
pubmed

Richter I, Hasan M, Kramer J, Wein P, Krabbe J, Wojtas P, Stinear T, Pidot S, Kloss F Hertweck C, Lackner G (2024) Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction. The ISME Journal. doi: 10.1093/ismejo/wrae074
pubmed

Bauer M, Soares M, Ermolaeva M, Singer M, Wetzker R (2024) Hormesis as an adaptive response to infection. Trends in Molecular Medicine. doi: 10.1016/j.molmed.2024.04.012
pubmed

Sharifi S, Chaudhari P, Martirosyan A, Eberhardt A, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli E, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff H, Ermolaeva M (2024) Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans. Nature Communications, doi: https://doi.org/10.1038/s41467-024-46037-w

Li H, Zhang L, Li J, Wu Q, Qian L, He J, Ni Y, Kovatcheva-Datchary P, Yuan R, Liu S, Shen L, Zhang M, Sheng B, Li P, Kang K, Wu L, Fang Q, Long X, Liu X, Wang X, Li Y, Ye Y, Ye J, Bao Y, Zhao Y, Xu G, Panagiotou G, Xu A, and Jia W (2024) Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota. Nature Metabolism. doi: https://doi.org/10.1038/s42255-024-00988-y
pubmed

Morabito G, Ryabova A, Valenzano DR (2024) Immune aging in annual killifish. Immunity & Ageing. doi: https://doi.org/10.1186/s12979-024-00418-3
pubmed

Kaden T, Alonso-Roman R, Akbarimoghaddam P, Mosig AS, Graf K, Raasch M, Hoffmann B, Figge MT, Hube B, Gresnigt MS, (2024) Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity. Biomaterials. doi: https://doi.org/10.1016/j.biomaterials.2024.122525
pubmed

Shankar-Hari M, Calandra T, Soares MP, Bauer M, et int., van der Poll T (2024) Reframing Sepsis Immunobiology for Translation. The Lancet Respiratory Medicine.
pubmed

Engel N, Hoffmann T, Behrendt F, Liebing P, Weber C, Gottschaldt M, Schubert US (2024) Cryogels Based on Poly (2-oxazoline) s through Development of Bi-and Trifunctional Cross-Linkers Incorporating End Groups with Adjustable Stability. Macromolecules. doi: https://doi.org/10.1021/acs.macromol.3c02030
pubmed

Kumar NH, Kluever V, Barth E, Krautwurst S, Furlan M, Pelizzola M, Marz M, et int., Fornasiero EF (2024) Comprehensive transcriptome analysis reveals altered mRNA splicing and post-transcriptional changes in the aged mouse brain. Nucleic Acids Research. doi: https://doi.org/10.1093/nar/gkae172
pubmed

Eberhardt N, Santamarina B, Enghardt M, Rohland O, Hussain I, Tannert A, Thieme L, Rubio I, Rödel J, Löffler B, Arndt H, Bauer M, Busch A, (2024) The effects of photoactivated ciprofloxacin and bile acids on biofilms on bile duct catheters. International Journal of Antimicrobial Agents, doi: https://doi.org/10.1016/j.ijantimicag.2024.107086

Loos D, Costa Filho AP, Dutilh BE, Barber AE, Panagiotou G (April 8, 2024) A global survey of host, aquatic, and soil microbiomes reveals shared abundance and genomic features between bacterial and fungal generalists. Cell Reports. doi: 10.1016/j.celrep.2024.114046
pubmed

Sekeresova Kralova J,…, Jansen P,…, Brunke S,…, Bacher P, Hube B, Shlezinger N, Jung S (2024) Competitive fungal commensalism mitigates candidiasis pathology. Journal of Experimental Medicine
pubmed

Carrasco Flores D, Hotter V, Vuong T, et int., Arndt HD, Hertweck C, Mittag M (Mar 11, 2024) A mutualistic bacterium rescues a green alga from an antagonist. PNAS. doi: https://doi.org/10.1073/pnas.2401632121
pubmed

Nakajima C et int. Arndt HD, et int., Sawamoto K (Mar 9, 2024) Identification of the growth cone as a probe and driver of neuronal migration in the injured brain. Nature Communications. doi: https://doi.org/10.1038/s41467-024-45825-8
pubmed

Ruhland E, Siemers M, Gerst R, Späth F, Vogt L, Figge M, Papenfort K, Fröhlich K (2024) The global RNA-RNA interactome of Klebsiella pneumoniae unveils a small RNA regulator of cell division. Proceedings of the National Academy of Sciences, doi: https://doi.org/doi:10.1073/pnas.2317322121

Mülller R, et int. Blango MG, Brakhage AA, et int. Hube B (Mar 9, 2024) Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences. Nat Microbiol. doi: 10.1038/s41564-024-01606-z
pubmed

Lucchetti M, et int. Mosig AS, Wilmes P (Mar 7, 2024) An Organ‐on‐chip Platform for Simulating Drug Metabolism along the Gut‐liver Axis. Advanced Healthcare Materials. doi: https://doi.org/10.1002/adhm.202303943
pubmed

Harnisch F, Deutzmann JS, Boto ST, Rosenbaum MA (Mar 1st, 2024) Microbial electrosynthesis: opportunities for microbial pure cultures. Trends in Biotechnology. doi: https://doi.org/10.1016/j.tibtech.2024.02.004
pubmed

Zulfiqar M, Singh V, Steinbeck C, Sorokina M (Jan 25, 2024) Review on computer-assisted biosynthetic capacities elucidation to assess metabolic interactions and communication within microbial communities. Critical Reviews in Microbiology. doi: https://doi.org/10.1080/1040841X.2024.2306465
pubmed

Hrovat K, Dutilh BE, Medema MH, Melkonian C (Jan 2024) Taxonomic resolution of different 16S rRNA variable regions varies strongly across plant-associated bacteria. ISME Communications. doi: https://doi.org/10.1093/ismeco/ycae034
pubmed

Alonso-Roman LR, Mosig AS, Figge MT, Papenfort K (2024) Organ-on-chip models for infectious disease research. Nature Microbiology. doi: https://doi.org/10.1038/s41564-024-01645-6
pubmed

Liang SH, Sircaik S, Dainis J, Kakade P, Penumutchu S, McDonough L, Chen YH, Frazer C, Schille T, Allert S, Elshafee O, Hänel M, Mogavero S, Vaishnava S, Cadwell K, Belenky P, Perez C, Hube B, Bennett RJ (2024) The hyphal-specific toxin candidalysin promotes fungal gut commensalism. Nature. doi: 10.1038/s41586-024-07142-4.
pubmed

Giamarellos-Bourboulis EJ, Aschenbrenner AC, Bauer M, et int., Weis S, Wiersinga J, Netea MG (Jan 2nd,2024) The pathophysiology of sepsis and precision-medicine-based immunotherapy. Nature Immunology. doi: https://doi.org/10.1038/s41590-023-01660-5
pubmed

Catalina-Hernández È, et int. Hellmich UA, et int., Perálvarez-Marín A (2024) Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold. CSBJ. doi: https://doi.org/10.1016/j.csbj.2023.12.028
pubmed

Behnke M, Vollrath A, Dahlke P, Larios FP, Chi M, Tsarenko E, Jordan PM, Weber C, Dirauf M, Czaplewska JA, Beringer-Siemers B, Stumpf S, Kellner C, Kretzer C, Hoeppener S, Nischang I, Sierka M, Eggeling C, Werz O, Schubert US (2024) PEtOxylated polyesteramide nanoparticles for the delivery of anti-inflammatory drugs. Materials Today Chemistry. doi: https://doi.org/10.1016/j.csbj.2023.12.028
pubmed

Stettin D, Pohnert G (2024) MSdeCIpher: A tool to link data from complementary ionization techniques in high-resolution GC-MS to identify molecular ions. Metabolites. doi: https://doi.org/10.3390/metabo14010010
pubmed

Dell M, Anh Tran M, Capper MJ, Sundaram S, Fiedler J, Koehnke J, Hellmich UA, Hertweck C (2024) Trapping of a polyketide synthase module after C-C bond formation reveals transient acyl carrier domain interactions. Angewandte Chem. Int. doi: https://doi.org/10.1002/anie.202315850
pubmed

Kumar G, Kallscheuer N, Kashif M, Ahamad S, Jagadeeshwari U, Pannikurungottu S, Haufschild T, Kabuu M, Sasikala C, Jogler C, Ramana CV (2024) Gemmata algarum, a novel Planctomycete isolated from an algal mat, displays antimicrobial activity. Marine Drugs. doi: https://doi.org/10.3390/md22010010
pubmed

2023

Yermakov O, Zeisberger M, Schneidewind H, Kim J, Bogdanov A, Kivshar Y, Schmidt M (2023) Advanced fiber in-coupling through nanoprinted axially symmetric structures. Applied Physics Reviews

Kumari P, Vasudevan S, Russo A, Wright S, Fraile-Ágreda V, Krajewski D, Jellison E, Rubio I, Bauer M, Shimoyama A, Fukase K, Zhang Y, Pachter J, Vanaja S, Rathinam V (2023)Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis. Nature Cell Biology, doi: https://doi.org/10.1038/s41556-023-01269-8
nature

Carrión O, Li C, Peng M, Wang J, Pohnert G, Azizah M, Zhu X, Curson A, Wang Q, Walsham K, Zhang X, Monaco S, Harvey J, Chen X, Gao C, Wang N, Wang X, Wang P, Giovanonni S, Zhang Y (2023) DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms. Nature Microbiology, doi:https://doi.org/10.1038/s41564-023-01526-4
nature

Kumari P, Vasudevan S, Russo A, Wright S, Fraile-Ágreda V, Krajewski D, Jellison E, Rubio I, Bauer M, Shimoyama A, Fukase K, Zhang Y, Pachter J, Vanaja S, Rathinam V (2023) Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis. Nature Cell Biology, doi: https://doi.org/10.1038/s41556-023-01269-8

Carrión O, Li C, Peng M, Wang, J, Pohnert G, Azizah M, Zhu X, Curson A, Wang Q, Walsham K, Zhang X, Monaco S, Harvey J, Chen X, Gao C, Wang N, Wang X, Wang P, Giovanonni S, Lee C, Suffridge C, Zhang Y, Luo, Z, Wang D, Todd J, Zhang Y (2023) DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms. Nature Microbiology, doi: https://doi.org/1038/s41564-023-01526-4

López JL, Fourie A, Poppeliers SWM, Pappas N, Sánchez-Gil JJ, de Jonge R, Dutilh BE (2023) Growth rate is a dominant factor predicting the rhizosphere effect. The ISME Journal, doi: https://doi.org/101038/s41396-023-01453-6.
pubmed

Heinze BM, Küsel K, Jehmlich N, von Bergen M, Taubert M (2023) Metabolic versatility enables sulfur-oxidizers to dominate primary production in groundwater. Water Research, doi: https://doi.org/101016/jtibs202207006.
pubmed

Stallforth P, Mittag M, Brakhage AA, Hertweck C, Hellmich UA (2023) Functional modulation of chemical mediators in microbial communities. Trends in Biochemical Sciences, doi: https://doi.org/101016/jtibs202207006.
pubmed

Jakob C, Lovate G L, Desirò D, Gießler L, Smyth Redmond P, Marquet R, Lamkiewicz K, Marz M, Schwemmle M, Bolte H (2023) Sequential disruption of SPLASH-identified vRNA–vRNA interactions challenges their role in influenza A virus genome packaging. Nucleic Acids Research, doi: https://doi.org/101093/nar/gkad442.
pubmed

Behrendt F, Deng Y, Pretzel D, Stumpf S, Fritz N, Gottschaldt M, Pohnert G, Schubert US (2023) Dimethylsulfoniopropionate decorated cryogels as synthetic spatially structured habitats of marine bacterial communities. Materials Horizons, doi: https://doi.org/101039/D2MH01383E.

Tugchin B, Doolaard N, Barreda A, Zhang Z, Romashkina A, Fasold S, Staude I, Eilenberger F, Pertsch T (2023) Photoluminescence Enhancement of Monolayer WS2 by n-Doping with an Optically Excited Gold Disk, Nano Letters, 2023,1021/acs.nanolett.3c03053

Fricke J, Schalk F, Kreuzenbeck N, Seibel E, Hoffmann J, Dittmann G, Conlon B, Guo H, Wilhelm de Beer Z, Vassão D, Gleixner G, Poulsen M, Beemelmanns C (2023) Adaptations of Pseudoxylaria towards a comb-associated lifestyle in fungus-farming termite colonies. The ISME Journal

Leonhardt J, Dorresteijn MJ, Neugebauer S, Mihaylov D, Kunze J, Rubio I, Hohberger F-S, Leonhardt S, Kiehntopf M, Stahl K, Bode C, David S, Wagener FADTG, Pickkers P, Bauer M (2023) Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk. Critical Care, doi: https://doi.org/101186/s13054-023-04620-5.
pubmed

López J, Fourie A, Poppeliers S, Pappas N, Sánchez-Gil J, de Jonge R, Dutilh B (2023) Growth rate is a dominant factor predicting the rhizosphere effect. The ISME Journal

Klapper FA, Kiel C, Bellstedt P, Vyverman W, Pohnert G (2023) Structure Elucidation of the First Sex-Inducing Pheromone of a Diatom. Angewandte Chemie International Edition, doi: https://doi.org/101002/anie202307165.
pubmed

Papenfort K, Melamed S (2023) Small RNAs, Large Networks: Posttranscriptional Regulons in Gram-Negative Bacteria. Annual Review of Microbiology

Bruggeling C, te Groen M, Garza D, van Heeckeren tot Overlaer F, Krekels J, Sulaiman B, Karel D, Rulof A, Schaaphok A, Hornikx D, Nagtegaal I, Dutilh B, Hoentjen F, Boleij A (2023) Bacterial Oncotraits Rather than Spatial Organization Are Associated with Dysplasia in Ulcerative Colitis. Journal of Crohn's and Colitis

von Meijenfeldt FAB, Hogeweg P, Dutilh BE (2023) A social niche breadth score reveals niche range strategies of generalists and specialists. Nature Ecology & Evolution, doi: https://doi.org/101038/s41559-023-02027-7.
pubmed

Mirhakkak MH, Chen X, Ni Y, Heinekamp T, Sae-Ong T, Xu L-L, Kurzai O, Barber AE, Brakhage AA, Boutin S, Schäuble S, Panagiotou G (2023) Genome-scale metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome. Nature Communications, doi: https://doi.org/101038/s41467-023-39982-5.
pubmed

Seelbinder B, Lohinai Z, Vazquez-Uribe R, Brunke S, Chen X, Mirhakkak M, Lopez-Escalera S, Dome B, Megyesfalvi Z, Berta J, Galffy G, Dulka E, Wellejus A, Weiss G J, Bauer M, Hube B, Sommer MOA, Panagiotou G (2023) Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions. Nature Communications, doi: https://doi.org/101038/s41467-023-38058-8.
pubmed

Lange T, Kasper L, Gresnigt, M, Brunke S, Hube B (2023)“Under Pressure” – How fungi evade, exploit, and modulate cells of the innate immune system. Seminars in Immunology

Chen J, Siliceo SL, Ni Y, Nielsen HB, Xu A, Panagiotou G (2023) Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions. Microbiome, doi: https://doi.org/101186/s40168-023-01604-z.
pubmed

Wegner C-E, Stahl R, Velsko I, Hübner A, Fagernäs Z, Warinner C, Lehmann R, Ritschel T, Totsche KU, Küsel K (2023) A glimpse of the paleome in endolithic microbial communities. Microbiome, doi: https://doi.org/101186/s40168-023-01647-2.
pubmed

Liu C, Eschen W, Loetgering L, Penagos Molina DS, Klas R, Iliou A, Steinert M, Herkersdorf S, Kirsche A, Pertsch T, Hillmann F, Limpert J, Rothhardt J (2023) Visualizing the ultra-structure of microorganisms using table-top extreme ultraviolet imaging. PhotoniX, doi: https://doi.org/101186/s43074-023-00084-6.

Krespach MKC, Stroe MC, Netzker T, Rosin M, Zehner LM, Komor AJ, Beilmann JM, Krüger T, Scherlach K, Kniemeyer O, Schroeckh V, Hertweck C, Brakhage AA (2023) Streptomyces polyketides mediate bacteria–fungi interactions across soil environments. Nature Microbiology, doi: https://doi.org/10.1038/s41564-023-01382-2.
pubmed

Jia L-J, Rafiq M, Radosa L, Hortschansky P, Cunha C, Cseresnyés Z, Krüger T, Schmidt F, Heinekamp T, Straßburger M, Löffler B, Doenst T, Lacerda JF, Campos A, Figge MT, Carvalho A, Kniemeyer O, Brakhage AA (2023) Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway. Cell Host & Microbe, doi: https://doi.org/101016/jchom202302002.
pubmed

Powell RE, Soares MP, Weis S (2023) What’s new in intensive care: disease tolerance. Intensive Care Medicine, doi: https://doi.org/101007/s00134-023-07130-8.
pubmed

Klapper M, Hübner A, Ibrahim A, Wasmuth I, Borry M, Haensch VG, Zhang S, Al-Jammal WK, Suma H, Fellows Yates JA, Frangenberg J, Velsko IM, Chowdhury S, Herbst R, Bratovanov EV, Dahse H-M, Horch T, Hertweck C, González Morales MR, Straus LG, Vilotijevic I, Warinner C, Stallforth P (2023) Natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic. Science, doi: https://doi.org/101126/scienceadf5300.
pubmed

Hellmich UA (2023) Dynamic ion channel defies dogma. Nature, doi: https://doi.org/10.1038/d41586-023-02486-9.
pubmed

Adriaenssens EM, Roux S, Brister JR, Karsch-Mizrachi I, Kuhn JH, Varsani A, Yigang T, Reyes A, Lood C, Lefkowitz EJ, Sullivan MB, Edwards RA, Simmonds P, Rubino L, Sabanadzovic S, Krupovic M, Dutilh BE (2023) Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification. Nature Biotechnology, doi: https://doi.org/101038/s41587-023-01844-2.
pubmed

Martini GR, Tikhonova E, Rosati E, DeCelie MB, Sievers LK, Tran F, Lessing M, Bergfeld A, Hinz S, Nikolaus S, Kümpers J, Matysiak A, Hofmann P, Saggau C, Schneiders S, Kamps A-K, Jacobs G, Lieb W, Maul J, Siegmund B, Seegers B, Hinrichsen H, Oberg H-H, Wesch D, Bereswill S, Heimesaat MM, Rupp J, Kniemeyer O, Brakhage AA, Brunke S, Hube B, Aden K, Franke A, Iliev ID, Scheffold A, Schreiber S, Bacher P (2023) Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn’s disease. Nature Medicine, doi: https://doi.org/101038/s41591-023-02556-5.
pubmed

Ni Y, Qian L, Leal Siliceo S, Long X, Nychas E, Liu Y, Ismaiah M, Leung H, Zhang L, Gao Q, Wu Q, Zhang Y, Jia X, Liu S, Yuan R, Zhou L, Wang X, Li Q, Zhao Y, El-Nezami H, Xu A, Xu G, Li H, Panagiotou G, and Jia W (2023) Resistant starch decreases intrahepatic triglycerides in patients with NAFLD via gut microbiome alteration. Cell Metabolism, doi: https://doi.org/10.1016/j.cmet.2023.08.002.
pubmed

Chao YY, Puhach A, Drieser D, Arunkumar M, Lehner L, Seeholzer T, Garcia-Lopez A, van der Wal M, Fibi-Smetanda S, Dietschmann A, Sommermann T, Ćiković T, Taher L, Gresnigt MS, Vastert SJ, van Wijk F, Panagiotou G, Krappmann D, Groß O, Zielinski C (2023) Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation. Nature Immunology, doi: 10.1038/s41561-022-00968-5.
pubmed

Gerst R, Cseresnyés Z, Figge MT (2023) JIPipe: visual batch processing for ImageJ. Nature Methods, doi: 10.1038/s41592-022-01744-4
pubmed

Götze S, Vij R, Burow K, Thome N, Urbat L, Schlosser N, Pflanze S, Müller R, Hänsch VG, Schlabach K, Fazlikhani L, Walther G, Dahse HM, Regestein L, Brunke S, Hube B, Hertweck C, Franken P, Stallforth P (2023) Ecological Niche-Inspired Genome Mining Leads to Discovery of Crop-Protecting Nonribosomal Lipopetides Featuring a Transient Amino Acid Building Block. J Am Chem Soc, doi: 10.1021/jacs.2c11107.
pubmed

Schwarz C, Eschenhagen P, Schmidt H, Hohnstein T, Iwert C, Frehn C, Roehmel J, Steinke E, Stahl M, Lozza L, Tikhonova E, Rosati E, Strevbo U, Babel N, Mainz JG, Wisplinghoff H, Ebel F, Jia LL, Blango MG, Hortschansky P, Brunke S, Hube B, Brakhage AA, Kniemeyer O, Scheffold A, Bacher P (2023) Antigen specifity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis. J Clin Invest, doi: 10.1172/JCI161593
pubmed

Orasch T, Gangapurwala G, Wollrath A, González K, Alex J, De San Luis A, Weber C, Hoeppener S, Cseresnyés Z, Figge MT, Guerrero-Sanchez C, Schubert US, Brakhage AA (2023). Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds. Biomater Adv, doi: 10.1016/j.bioadv.2023.213300.
pubmed

Petrollo S, De Giorgio F, Garello F, Bitonto V, Longo DL, Mercurio S, Ammirata G, Allocco AL, Fiorito V, Chiabrando D, Altruda F, Terreno E, Provero P, Munaron L, Genova T, Nóvoa A, Carlos AR, Cardoso S, Mallo M, Soares MP, Tolosan E (2023) Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis. Angiogenesis, doi: 10.1007/s10456-023-09865-w.
pubmed

2022

Murillo-Roos M, Abdullah H, Debbar M, Ueberschaar N, Agler M (2022) Cross-feeding niches among commensal leaf bacteria are shaped by the interaction of strain-level diversity and resource availability. The ISME Journal

Huber M, Lippegaus A, Melamed S, Siemers M, Wucher B, Hoyos M, Nadell C, Storz G, Papenfort K (2022) An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae. Nature communications

Bloos F, Held J, Kluge S, Simon P, Kogelmann K, de Heer G, Kuhn S, Motsch J, Hempel G, Weiler N, Weyland A, Drüner M, Meybohm P, Jaschinski U, Moerer O, Günther U, Schädler D, Weiss R, Putensen C, Castellanos I, Kurzai O, Schlattmann P, Cornely O, Jaschinski U, Putensen C, Drüner M, Castellanos I, Schmidt S, Wehrfritz A, Kränzlein D, Held J, Zacharowski K, Mutlak H, Lindau S, Wiedenbeck C, Mörer O, Gründling M, Kluge S, de Heer G, Jarczak D, Motsch J, Richter D, Weigand M, Bauer M, Thomas-Rüddel D (2022) (1 → 3)-β-d-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. Intensive Care Medicine

Zub K, Hoeppener S, Schubert U (2022) Inkjet Printing and 3D Printing Strategies for Biosensing, Analytical, and Diagnostic Applications. Advanced Materials

Li X, Leonardi I, Putzel G, Semon A, Fiers W, Kusakabe T, Lin W, Gao I, Doron I, Gutierrez-Guerrero A, DeCelie M, Carriche G, Mesko M, Yang C, Naglik J, Hube B, Scherl E, Iliev I (2022). Immune regulation by fungal strain diversity in inflammatory bowel disease. Nature

Günther M, Reimer C, Herbst R, Stallforth P (2022). Yellow polyketide pigment suppresses premature hatching in social amoeba. PNAS, doi: 119 (43) e2116122119
pubmed

Overholt WA, Trumbore S, Xu X, Bornemann TLV, Probst AJ, Krüger M, Herrmann M, Thamdrup B, Bristow LA, Taubert M, Schwab VF, Hölzer M, Marz M, Küsel K (2022). Carbon fixation in groundwater similar to those in oligotrophic marine systems. Nature Geoscience, doi: 10.1038/s41561-022-00968-5.
pubmed

Ramos S, Ademoloue, TW, Jentho E, Wu Q, Guerra J, Martins R, Pires G, Weis S, Carlos AR, Mahú I, Seixas E, Duarte D, Rajas F, Cardoso S, Sousa AGG, Lilue J, Paixao T, Mithieux G, Nogueira F, Soares MP (2022) A hypometabolic defense strategy against malaria. Cell Metabolism, doi: 10.1016/j.cmet.2022.06.011
pubmed

Gude F, Molloy E, Hoch T, Dell M, Dunbar K, Krabbe J, Groll M, Hertweck C (2022) A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria. Angewandte Chemie, doi: 10.1002/anie.202206168.
pubmed

Stallforth P, Mittag M, Brakhage AA, Hertweck C, Hellmich UA (2022) Functional modulation of chemical mediators in microbial communities. Trends in Biochemical Sciences, doi: 10.1016/j.tibs.2022.07.006
pubmed

Andrades Valtueña A, Neumann G, Spyrou M, Musralina L, Aron F, Beisenov A, Belinskiy A, Bos K, Buzhilova A, Conrad M, Djansugurova L, Dobeš M, Ernée M, Fernández-Eraso J, Frohlich B, Furmanek M, Hałuszko A, Hansen S, Harney É, Hiss A, Hübner A, Key F, Khussainova E, Kitov E, Kitova A, Knipper C, Kühnert D, Lalueza-Fox C, Littleton J, Massy K, Mittnik A, Mujika-Alustiza J, Olalde I, Papac L, Penske S, Peška J, Pinhasi R, Reich D, Reinhold S, Stahl R, Stäuble H, Tukhbatova R, Vasilyev S, Veselovskaya E, Warinner C, Stockhammer P, Haak W, Krause J, Herbig A (2022) Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague. Proceedings of the National Academy of Sciences

Ding Y, So B, Cao J, Wondraczek L (2022) Ultrasound-Induced Mechanoluminescence and Optical Thermometry Toward Stimulus-Responsive Materials with Simultaneous Trigger Response and Read-Out Functions. Advanced Science, doi: 10.1002/advs.202201631
pubmed

Hauptfeld E, Pelkmans J, Huisman T, Anocic A, Snoek B, von Meijenfeldt B, Gerritse J, van Leeuwen J, Leurink G, van Lit A, van Uffelen R, Koster M, Dutilh B (2022) A metagenomic portrait of the microbial community responsible for two decades of bioremediation of poly-contaminated groundwater. Water Research

Zhu B, Wei D, Pohnert G (2022). The thermoacidophilic red alga Galdieria sulphuraria is a highly efficient cell factory for ammonium recovery from ultrahigh-NH4+ industrial effluent with co-production of high-protein biomass by photo-fermentation. Chemical Engineering Journal, doi: 10.1016/j.cej.2022.135598.
ScienceDirect

Polley N, Sardar S, Werner P, Gersonde I, Kanehira Y, Bald I, Repp D, Pertsch T, Pacholski C (2022) Photothermomechanical Nanopump: A Flow-Through Plasmonic Sensor at the Fiber Tip. ACS Nano

Siwczak F, Cseresnyes Z, Carlstedt S, Sigmund A, Gröger M, Surewaard B, Werz O, Figge M, Tuchscherr L, Löffler B, Mosig A (2022) Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model. Biomaterials

Zerfaß C, Lehmann R, Ueberschaar N, Sanchez-Arcos C, Totsche K, Pohnert G (2022)Groundwater metabolome responds to recharge in fractured sedimentary strata. Water Research

Hoang T, Cseresnyés Z, Hartung S, Blickensdorf M, Saffer C, Rennert K, Mosig A, von Lilienfeld-Toal M, Figge M (2022) Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection. Biomaterials

Velsko I, Semerau L, Inskip S, García-Collado M, Ziesemer K, Ruber M, Benítez de Lugo Enrich L, Molero García J, Valle D, Peña Ruiz A, Salazar-García D, Hoogland M, Warinner C (2022) Ancient dental calculus preserves signatures of biofilm succession and interindividual variation independent of dental pathology. PNAS Nexus

Zhang L, Simonsen C, Zimova L, Wang K, Moparthi L, Gaudet R, Ekoff M, Nilsson G, Hellmich U, Vlachova V, Gourdon P, Zygmunt P (2022) Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function, Nature communications

Portwich F, Carstensen Y, Dasgupta A, Kupfer S, Wyrwa R, Görls H, Eggeling C, Dietzek B, Gräfe S, Wächtler M, Kretschmer R (2022) A Highly Fluorescent Dinuclear Aluminium Complex with Near-Unity Quantum Yield**. Angewandte Chemie International Edition

Huang Y, Hoefgen S, Gherlone F, Valiante V (2022) Intrinsic Ability of the β-Oxidation Pathway To Produce Bioactive Styrylpyrones. Angewandte Chemie International Edition

Alonso-Roman R, Last A, Mirhakkak MH, Sprague JL, Möller L, Großmann P, Graf K, Gratz R, Mogavero S, Vylkova S, Panagiotou G, Schäuble S, Hube B, Gresnigt MS (2022) Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptions that compromise pathogenicity. Nature Communications, doi: 10.1038/s41467-022-30661-5
pubmed

Leung H, Long X, Ni Y, Qian L, Nychas E, Leal Siliceo S, Pohl D, Hanhineva K, Liu Y, Xu A, Nielsen HB, Belda E, Clément K, Loomba R, Li H, Jia W, Panagiotou G (2022) Risk assessment with gut microbiome and metabolite markers in NAFLD development. Science Translational Medicine, doi: 10.1126/scitranslmed.abk0855
pubmed

De Almeida GP, Lichtner P, Eckstein G, Brinkschmidt T, Chu CF, Sun S, Reinhard J, Maedler SC, Kloeppel M, Verbeek M, Zielinski CE (2022) Human skin-resident host T cells can persist long term after allogeneic stem cell transplantation and maintain recirculation potential. Science Immunology, doi: 10.1126/sciimmunol.abe2634.
pubmed

Westman J, Plumb J, Licht A, Yang M, Allert S, Naglik JR, Hube B, Grinstein S, Maxson ME (2022) Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion. Cell Reports, doi: 10.1016/j.celrep.2021.110187.
pubmed

Deng Y, Vallet M, Pohnert G (2022) Temporal and spatial signaling mediating the balance of the plankton microbiome. Ann Rev Mar Sci, doi: 10.1146/annurev-marine-042021-012353.
pubmed

2021

Gressler M, Löhr N, Schäfer T, Lawrinowitz S, Seibold P, Hoffmeister D (2021) Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota. Natural Product Reports

Barber A, Sae-Ong T, Kang K, Seelbinder B, Li J, Walther G, Panagiotou G, Kurzai O (2021) Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection. Nature Microbiology

Traxler L, Shrestha J, Richter M, Krause K, Schäfer T, Kothe E (2021) Metal adaptation and transport in hyphae of the wood-rot fungus Schizophyllum commune. J Hazard Mater., doi: 10.1016/j.jhazmat.2021.127978 .
pubmed

Wu Y, Zeng Z, Guo Y, Song L, Weatherhead JE, Huang X, Zeng Y, Bimler L, Chang CY, Knight JM, Valladolid C, Sun H, Cruz MA, Hube B, Naglik JR, Luong AU, Kheradmand F, Corry DB (2021) Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarization. Immunity, doi: 10.1016/j.immuni.2021.08.009.
pubmed

Marfil-Sánchez A, Zhang L, Alonso-Pernas P, Mirhakkak M, Mueller M, Seelbinder B, Ni Y, Santhanam R, Busch A, Beemelmanns C, Ermolaeva M, Bauer M, Panagiotou G (2021) An integrative understanding of the large metabolic shifts induced by antibiotics in critical illness. Gut Microbes, doi: 10.1080/19490976.2021.1993598.
pubmed

Taubert M, Overholt WA, Heinze BM, Matanfack GA, Houhou R, Jehmlich N, von Bergen M, Rösch P, Popp J, Küsel K (2021) Bolstering fitness via CO2 fixation and organic carbon uptake: mixotrophs in modern groundwater. ISME J, doi: 10.1038/s41396-021-01163-x.
pubmed

Krespach M, Stroe MC, Flak M, Kornor AJ, Nietzsche S, Sasso S, Hertweck C, Brakhage AA (2021) Bacterial marginolactones trigger formation of algal gloeocapsoids, protective aggregates on the verge of multicellularity. PNAS, doi: 10.1073/pnas.2100892118.
pubmed - This work was funded by the CRC 1127

Jentho E, Ruiz-Moreno C, Novakovic B, Kourtzelis I, Megchelenbrink W, Martins R, Chavakis T, Soares MP, Kalafati L, Guerra J, Roestel F, Bohm P, Godmann M, Grinenko T, Eugster A, Beretta M, Joosten L, Netea M, Bauer M, Stunnberg H, Weis S (2021) Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme. PNAS, doi: 10.1073/pnas.2102698118.
pubmed

Venkat K, Hoyos M, Haycocks J, Cassidy L, Engelmann B, Rolle-Kampczyk U, von Bergen M, Tholey A, Grainger D, Papenfort K (2021) A dual-function RNA balances carbon uptake and central metabolism in Vibrio cholerae. EMBO J, doi: 10.15252/embj.2021108542.
pubmed

Büttner H, Niehs SP, Vandelannoote K, Cseresnyés Z, Dose B, Richter I, Gerst R, Figge MT, Stinear TP, Pidot SJ, Hertweck C (2021) Bacterial endosymbionts protect beneficial soil fungus from nematode attack. PNAS, doi: 10.1073/pnas.2110669118.
pubmed

Press AT, Babic P, Hoffmann B, Müller T, Foo W, Hauswald W, Benecke J, Beretta M, Cseresnyés Z, Hoeppener S, Nischang I, Coldewey SM, Gräler MH, Bauer R, Gonnert F, Gaßler N, Wetzker R, Figge MT, Schubert US, Bauer M (2021) Targeted delivery of a phosphoinositide 3-kinase y inhibitor to restore organ function in sepsis. EMBO Molecular Medicine, doi: 10.15252/emmm.202114436.
pubmed

Little RF, Hertweck C (2021) Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. Natural Product Reports, doi: 10.1039/d1np00035g.
pubmed

Nozari V, Calahoo C, Tuffnell J, Keen D, Bennett T, Wondraczek L (2021) Ionic Liquid Facilitated Melting of the Metal-Organic Framework ZIF-8. Nature communications

Schmidt S, Kildgaard S, Guo HJ, Beemelmanns C, Poulsen M (2021) The chemical ecology of the fungus-farming termite symbiosis. Natural Product Reports, doi: 10.1039/d1np00022e.
pubmed

Scherlach K, Hertweck C (2021) Mining and unearthing hidden biosynthetic potential. Nature Communications, doi: 10.1038/s41467-021-24133-5.
pubmed

Zhang J, Ni Y, Qian L, Fang Q, Zheng T, Zhang M, Gao Q, Zhang Y, Ni J, Hou X, Bao Y, Kovatcheva Datchary P, Xu A, Li H, Panagiotou G, Jia W (2021) Decreased abundance of Akkermansia muciniphila leads to the impairment of insulin secretion and glucose homeostasis in lean type 2 diabetes. Advanced Science, doi: 10.1002/advs.202100536.
pubmed

Helk T, Berger E, Jamnuch S, Hoffmann L, Kabacinski A, Gautier J, Tissandier F, Goddet JP, Chang HT, Oh J, Pemmaraju CD, Pascal TA, Sebban S, Spielmann C, Zuerch M (2021) Table-top extreme ultraviolet second harmonic generation. Science Advances, doi: 10.1126/sciadv.abe2265.
pubmed

Ni Y, Lohinai Z, Heshiki Y, Dome B, Moldavy J, Dulka E, Galffy G, Berta J, Weiss GJ, Sommer MOA, Panagiotou G (2021) Distinct composition and metabolic functions of human gut microbiota are associated with cachexia in lung cancer patients. ISME J, doi: 10.1038/s41396-021-00998-8.
pubmed

Yan L, Hermans S, Totsche K, Lehmann R, Herrmann M, Küsel K (2021) Groundwater bacterial communities evolve over time in response to recharge. Water Research, doi: 10.1016/j.watres.2021.117290.
pubmed

Wibowo MC, Yang Z, Borry M, Hübner A, Huang KD, Tierney BT, Zimmerman S, Barajas Olomos F, Contreras Cubas C, García Ortiz H, Martínez Hernández A, Luber JM, Kirstahler P, Blohm T, Smiley FE, Arnold R, Ballal SA, Pamp SJ, Russ J, Maixner F, Rota Stabelli O, Segata N, Reinhard K, Orozco L, Warinner C, Snow M, LeBlanc S, Kostic AD (2021) Reconstruction of ancient microbial genomes from the human gut. Nature, doi: 10.1038/s41586-021-03532-0.
pubmed

Fellows Yates JA, Velsko IM, Aron F, Posth C, Hofman CA, Austin RM, Parker CE, Mann AE, Nägele K, Arthur JW, Bauer CC, Crevecoeur I, Cupillard C, Curtis MC, Dalén L, Diáz Zorita Bonilla M, Diéz Fernández Lomana JC, Drucker DG, Escribano Escrivá E, Francken M, Gibbon VE, González Morales MR, Grande Mateu A, Harvati K, Henry AG, Humphrey L, Menéndez M, Mihailovic D, Peresani M, Rodríguez Moroder S, Roksandic M, Rougier H, Sázelová S, Stock JT, Guy Straus L, Svoboda J, Teßmann B, Walker MJ, Power RC, Lewis CM, Sankaranarayanan K, Guschanski K, Wrangham RW, Dewhirst FE, Salazar García DC, Krause J, Herbig A, Warinner C (2021) The evolution and changing ecology of the African hominid oral microbiome. PNAS, doi: 10.1073/pnas.2021655118.
pubmed

Molloy EM, Dell M, Hänsch VG, Dunbar K, Feldmann R, Oberheide A, Seyfarth L, Kumpfmüller J, Horch T, Arndt HD, Hertweck C (2021) Enzyme-primed negative chemical ligation produces autoinducing cyclopeptides in Clostridia. Angew Chem Int Ed Engl, doi: 10.1002/anie.202016378.
pubmed

Gilaberte Basset M, Hochrainer A, Töpfer S, Riexinger F, Bickert P, León Torres JR, Steinlechner F, Gräfe M (2021) Video-Rate Imaging with Undetected Photons. Laser & Photonics Reviews, doi: 10.1002/lpor.202000327.
Wiley

Singh S, Thompson JA, Yilmaz B, Li H, Weis S, Sobral D, Truglio M, Aires da Silva F, Aguiar S, Carlos AR, Rebelo S, Cardoso S, Gjini E, Nuñez G, Soares MP (2021) Loss of α-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis. Cell Host Microbe S1931-3128(20)30680-6.
pubmed

Zhang S, Mukherji R, Chowdhury S, Reimer L, Stallforth P (2021) Lipopeptide-mediated bacterial interaction enables cooperative predator defense. PNAS 118(6):e2013759118.
pubmed

Schlembach I, Grünberger A, Rosenbaum MA, Regestein L (2021) Measurement Techniques to Resolve and Control Population Dynamics of Mixed-Culture Processes. Trends Biotechnol. S0167-7799(21)00012-3.
pubmed

Last A, Maurer M, Mosig AS, Gresnigt MS, Hube B (2021) In vitro infection models to study fungal-host interactions. FEMS Microbiol Rev, doi: 10.1093/femsre/fuab005.
pubmed

Russo AJ, Vasudevan SO, Méndez Huergo SP, Kumari P, Menoret A, Duduskar S, Wang C, Pérez Sáez JM, Fettis MM, Li C, Liu R, Wanchoo A, Chandiran K, Ruan J, Kailasan Vanaja SK, Bauer M, Sponholz C, Hudalla GA, Vella AT, Zhou B, Deshmukh SD, Rabinovich GA, Rathinam VA (2021) Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin. Nature Immunology, doi: 10.1038/s41590-020-00844-7.
pubmed

2020

Haange S, Jehmlich N, Krügel U, Hintschich C, Wehrmann D, Hankir M, Seyfried F, Froment J, Hübschmann T, Müller S, Wissenbach D, Kang K, Buettner C, Panagiotou G, Noll M, Rolle-Kampczyk U, Fenske W, von Bergen M (2020) Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss, Microbiome

Martin-Loeches I, Dickson R, Torres A, Hanberger H, Lipman J, Antonelli M, de Pascale G, Bozza F, Vincent J, Murthy S, Bauer M (2020) The importance of airway and lung microbiome in the critically ill. Critical care

Chu H, Duan Y, Lang S, Jiang L, Wang Y, Llorente C, Liu J, Mogavero S, Bosques-Padilla F, Abraldes J, Hube B (2020) The Candida albicans exotoxin candidalysin promotes alcohol-associated liver disease. Journal of hepatology

Liu Y, Wang Y, Ni Y, Cheung C, Lam K, Wang Y, Xia Z, Ye D, Guo J, Tse M, Panagiotou G (2020) Gut microbiome fermentation determines the efficacy of exercise for diabetes prevention. Cell metabolism

Neubacher N, Tobias NJ, Huber M, Cai X, Glatter T, Pidot SJ, Stinear TP, Lütticke AL, Papenfort K, Bode HB (2020) Symbiosis, virulence and natural-product biosynthesis in entomopathogenic bacteria are regualted by a small RNA. Nat Microbiol 5(12):1481-1489.
pubmed

Peschek N, Herzog R, Singh PK, Sprenger M, Meyer F, Fröhlich KS, Schröger L, Bramkamp M, Drescher K, Papenfort K (2020) RNA-mediated control of cell shape modulates antibiotic resistance in Vibrio cholerae. Nat Commun 11(1):6067.
pubmed

Flores DC, Fricke M, Wesp V, Desirò D, Kniewasser A, Hölzer M, Marz M, Mittag M (2020) A marine Chlamydomonas sp. emerging as an algal model. J Phycol 57(1):54-69.
pubmed

Borowiak M, Küllmer F, Gegenfurtner F, Peil S,  Nasufovic V, Zahler S, Thorn-Seshold O, Trauner D, Arndt HD (2020) Optical manipulation of F-Actin with photoswitchable small molecules. J Am Chem Soc 142(20):9240-9249.
pubmed

Rak LS, Schalk F, Schwitalla JW, Benndorf R, Vollmers J, Kaster AK, de Beer ZW, Park M, Ahn MJ, Jung WH, Beemelmanns C, Kim KH (2020) Polyhalogenation of isoflavonoids by the termite-associated Actinomadura sp. RB99. J Nat Prod 83(10):3102-3110.
pubmed

d'Enfert C, Kaune A, Alaban L, Chakraborty S, Cole N, Delavy M, Kosmala D, Marsaux B, Fróis-Martins R, Morelli M, Gresnigt M, Hube B, Jacobsen I (2020) The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives. FEMS Microbiology Reviews

Haange S, Jehmlich N, Krügel U, Hintschich C, Wehrmann D, Hankir M, Seyfried F, Froment J, Hübschmann T, Müller S, Panagiotou G (2020) Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss. Microbiome

Diederich B, Helle Ø, Then P, Carravilla P, Schink K, Hornung F, Deinhardt-Emmer S, Eggeling C, Ahluwalia B, Heintzmann R (2020) Nanoscopy on the Chea(i)p. bioRxiv

Diederich B, Lachmann R, Carlstedt S, Marsikova B, Wang H, Uwurukundo X, Mosig A, Heintzmann R (2020) A versatile and customizable low-cost 3D-printed open standard for microscopic imaging. Nature communications

Seelbinder B, Chen J, Brunke S, Vazquez-Uribe R, Santhaman R, Meyer AC, Senne de Oliveira Lino F, Chan KF, Loos D, Imamovic L, Tsang CC, Puikin Lam R, Sridhar S,  Kang K, Hube B, Woo PC, Sommer MOA, Panagiotou G (2020) Antibiotics create a shift from mutualism to competetion in human gut communities with a longer lasting impact on fungi than bacteria. Microbiome 8(1):133.
pubmed

Azemtsop Matanfack G, Taubert M, Guo S, Houhou R, Bocklitz T, Küsel K, Popp J (2020) Influence of  carbon sources on quantification of deuterium incorporation in heterotrophic bacteria: a raman-stable isotope labeling approach. Analytical Chemistry 92(16):11429-11437.
pubmed

Hoyos M, Huber M, Förstner KU, Papenfort K (2020) Gene autoregulation by 3' UTR-derived bacterial small RNAs. eLife 9:e58836.
pubmed

Krespach MKC, García-Altares M, Flak M, Schoeler H, Scherlach K, Netzker T, Schmalzl A, Mattern DJ, Schroeckh V, Komor A, Mittag M, Hertweck C, Brakhage AA (2020) Lichen-like association of Chlamydomonas reinhardtii and Aspergillus nidulas protects algal cells from bacteria. ISME 14(11):2794-2805.
pubmed

Schmidt F, Thywißen A, Röcker M, Cunha C, Cseresnyés Z, Schmidt H, Galiani S, Gräler MH, Chamilos G, Lacerda JF, Campos AJ, Eggeling C, Figge MT, Heinekamp T, Filler SG, Carvalho A, Brakhage AA (2020) Flotillin-dependent lipid-raft microdomains are required for functional phagolysosomes against fungal infections. Cell Reports 32(7):108017.
pubmed

Kohn T, Rast P, Kallschuer N, Wiegand S, Boedeker C, Jetten MSM, Jeske O, Vollmers J, Kaster AK, Rohde M, Jogler M, Jogler C (2020) The microbiome of Posidonia oceania seagrass leaves can be dominated by planctomycetes. Front Microbiol 11:1458.
pubmed

Gao C, Fernandez VI, Lee KS, Fenizia S, Pohnert G, Seymour JR, Raina JB, Stocker R (2020) Single-cell bacterial transcription measurements reveal the importance of dimethylsulfoniopropionate (DMSP) hotspots in ocean sulfur cycling. Nat Commun 11(1):1942.
pubmed

Huber M, Fröhlich KS, Radmer J, Papenfort K (2020) Switching fatty acid metabolism by an RNA-controlled feed forward loop. PNAS 117(14):8044-8054.
pubmed

Heshiki Y, Vazquez-Uribe R, Li Ji, Ni Y, Quainoo S, Imamovic L, Li Ju, Sørensen M, Chow BKC, Weiss GJ, Xu A, Sommer MOA, Panagiotou G (2020) Predictable modulation of cancer treatment outcomes by the gut microbiota. Microbiome, doi: 10.1186/s40168-020-00811-2.
pubmed

Yan L, Herrmann M, Kampe B, Lehmann R, Totsche KU, Küsel K (2020) Environmental selection shapes the formation of near-surface groundwater microbiomes. Water Res 8(1):28.
pubmed

Deinhardt-Emmer S, Rennert K, Schicke E, Cseresnyés Z, Windolph M, Nietzsche S, Heller R, Siwczak F, Haupt KF, Carlstedt S, Schacke M, Figge MT, Ehrhardt C, Löffler B, Mosig AS (2020) Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model. Biofabrication 12(2):025012.
pubmed

Niehs SP, Dose B, Richter S, Pidot SJ, Dahse HM, Stinear TP, Hertweck C (2020) Mining symbionts of a spider-transmitted fungus illuminates unchartered biosynthetic pathways to cytotoxic benzolactones. Angew Chem Int Ed Engl 59(20):7766-7771.
pubmed

Stroe MC, Netzker T, Scherlach K, Krüger T, Hertweck C, Valiante V, Brakhage AA (2020) Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin. eLife 9:e52541.
pubmed

Mukherji R, Zhang S, Chowdhury S, Stallforth P (2020) Chimeric LuxR transcription factors rewire natural product regulation. Angew Chem Int Ed 59(15):6192-6195.
pubmed

2019

Maurer M, Gresnigt M, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Groeger M, Jacobsen I, Figge M, Hube B, Mosig A (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials

Cirri E, Pohnert G (2019) Algae− bacteria interactions that balance the planktonic microbiome. New Phytologist

Chen J, McIlroy S, Archana A, Baker D, Panagiotou G (2019) A pollution gradient contributes to the taxonomic, functional, and resistome diversity of microbial communities in marine sediments. Microbiome

Bedard M, Shrestha D, Priestman D, Wang Y, Schneider F, Matute J, Iyer S, Gileadi U, Prota G, Kandasamy M, Eggeling C (2019) Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells. Proceedings of the National Academy of Sciences

Favard C, Chojnacki J, Merida P, Yandrapalli N, Mak J, Eggeling C, Muriaux D (2019) HIV-1 Gag specifically restricts PI (4, 5) P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly. Science advances

Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietsch S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220:119396.
pubmed

Trottmann F, Franke J, Richter I, Ishida K, Cyrulies M, Dahse HM, Regestein L, Hertweck C (2019) Cyclopropanol warhead in malleicyprol confers virulence of human- and animal-pathogenic Burkholderia species. Angew Chem Int Ed 58(40): 14129-14133.
pubmed

Vallet M, Baumeister TUH, Kaftan F, Grabe V, Buaya A, Thines M, Svatoš A, Pohnert G (2019) The oomycete Lagenisma coscinodisci hijacks host alkaloid synthesis during infection of a marine diatom. Nat Commun 10(1): 4938.
pubmed

Wondraczek L, Pohnert G, Schacher FH, Köhler A, Gottschaldt M, Schubert US, Küsel K, Brakhage AA (2019) Artificial Microbial Arenas: Materials for Observing and Manipulating Microbial Consortia. Adv Mater 31(24):e1900284, doi: 10.1002/adma.201900284.
pubmed

Bacher P, Hohnstein T, Beerbaum E, Röcker M, Kaufmann S, Brandt C, Röhmel J, Stervbo U, Nienen M, Babel N, Milleck J, Assenmacher M, Cornely OA, Heine G, Worm M, Creutz P, Tabeling C, Ruwwe-Glösenkamp C, Sander LE, Brunke S, Hube B, Blango M, Kniemeyer O, Brakhage AA, Schwarz C, Scheffold A (2019) Human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans. Cell 176(6): 1340-1355.e15.
pubmed

Previous

2018

Thume K, Gebser B, Chen L, Meyer N, Kieber DJ, Pohnert G (2018) The metabolite dimethylsulfoxonium propionate extends the marine organosulfur cycle. Nature 563: 412-5.
pubmed

Stappers MHT, Clark AE, Aimanianda V, Bidula S, Reid DM, Asamaphan P, Hardison SE, Dambuza IM, Valsecchi I, Kerscher B, Plato A, Wallace CA, Yuecel R, Hebecker B, da Glória Teixeira Sousa M, Cunha C, Liu Y, Feizi T, Brakhage AA, Kwon-Chung KJ, Gow NAR, Zanda M, Piras M, Zanato C, Jaeger M, Netea MG, van de Veerdonk FL, Lacerda JF, Campos A, Carvalho A, Willment JA, Latgé JP, Brown GD (2018) Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus. Nature 555: 382-6
pubmed

Hermenau R, Ishida K, Gama S, Hoffmann B, Pfeifer-Leeg M, Plass W, Mohr JF, Wichard T, Saluz HP, Hertweck C (2018) Gramibactin is a bacterial siderophore with a diazeniumdiolate ligand system. Nat Chem Biol 14: 841-3.
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Vågene ÅJ, Herbig A, Campana MG, Robles García NM, Warinner C, Sabin S, Spyrou MA, Andrades Valtueña A, Huson D, Tuross N, Bos KI, Krause J (2018) Salmonella enterica genomes from victims of a major sixteenth-century epidemic in Mexico. Nat Ecol Evol 2: 520-8.
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Dunbar KL, Büttner H, Molloy EM, Dell M, Kumpfmüller J, Hertweck C (2018) Genome editing reveals novel thiotemplated assembly of polythioamide antibiotics in anaerobic bacteria. Angew Chem Int Ed 57: 14080-4.
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Englert C, Nischang I, Bader C, Borchers P, Alex J, Pröhl M, Hentschel M, Hartlieb M, Träger A, Pohnert G, Schubert S, Gottschaldt M, Schubert US (2018) Photocontrolled release of chemicals from nano- and microparticle containers. Angew Chem Int Ed 57: 2479-82.
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Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbancic I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF (2018) Capturing resting T cells: the perils of PLL. Nat Immunol 19: 203-5.
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2017

Weis S, Carlos AR, Moita MR, Singh S, Blankenhaus B, Cardoso S, Larsen R, Rebelo S, Schauble S, Del Barrio L, Mithieux G, Rajas F, Lindig S, Bauer M, Soares MP (2017) Metabolic adaptation establishes disease tolerance to sepsis. Cell 169: 1263-75.
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Fritzsche M, Li D, Colin-York H, Chang VT, Moeendarbary E, Felce JH, Sezgin E, Charras G, Betzig E, Eggeling C (2017) Self-organizing actin patterns shape membrane architecture but not cell mechanics. Nat Commun 8: 14347.
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Aiyar P, Schaeme D, García-Altares M, Carrasco Flores D, Dathe H, Hertweck C, Sasso S, Mittag G (2017) Antagonistic bacteria disrupt calcium homeostasis and immobilize algal cells. Nat Commun 8: 1756.
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Sollapur R, Kartashov D, Zürch M, Hoffmann A, Grigorova T, Sauer G, Hartung A, Schwuchow A, Bierlich J, Kobelke J, Chemnitz M, Schmidt MA, Spielmann C (2017) Resonance-enhanced multi-octave supercontinuum generation in antiresonant hollow-core fibers. Light Sci Appl 6: e17124.
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2016

Moyes DL, Wilson D, Richardson JP, Mogavero S, Tang SX, Wernecke J, Höfs S, Gratacap RL, Robbins J, Runglall M, Murciano C, Blagojevic M, Thavaraj S, Förster TM, Hebecker B, Kasper L, Vizcay G, Iancu SI, Kichik N, Häder A, Kurzai O, Luo T, Krüger T, Kniemeyer O, Cota E, Bader O, Wheeler RT, Gutsmann T, Hube B, Naglik JR (2016) Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature 532: 64-8.
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Bacher P, Heinrich F, Stervbo U, Nienen M, Vahldieck M, Iwert C, Vogt K, Kollet J, Babel N, Sawitzki B, Schwarz C, Beereswill S, Heimesaat M, Heine G, Gadermaier G, Asam C, Assenmacher M, Kniemeyer O, Brakhage AA, Ferreira-Briza F, Wallner M, Worm M, Scheffold A (2016) Regulatory T cell specificity directs tolerance versus allergy against aeroantigens in humans. Cell 167: 1067-78.
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Beulig F, Urich T, Nowak M, Trumbore SE, Gleixner G, Gilfillan GD, Fjelland KE, Küsel K (2016) Altered carbon turnover processes and microbiomes in soils under long-term extremely high CO2 exposure. Nat Microbiol 1: 15025.
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Winter S, Jahn K, Wehner S, Kuchenbecker L, Marz M, Stoye J, Böcker S (2016) Finding approximate gene clusters with Gecko 3. Nucleic Acids Res 44: 9600-10.
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Petroutsos D, Tokutsu R, Maruyama S, Flori S, Greiner A, Magneschi L, Cusant L, Kottke T, Mittag M, Egemann P, Finazzi G, Minagawa J (2016) A blue-light photoreceptor mediates the feedback regulation of photosynthesis. Nature 537: 563-6.
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Wohlgemuth G, Mehta SS, Mejia RF, Neumann S, Pedrosa D, Pluskal T, Schymanski EL, Willighagen EL, Wilson M, Wishart DS, Arita M, Dorrestein PC, Bandeira N, Wang M, Schulze T, Salek RM, Steinbeck C, Nainala VC, Mistrik R, Nishioka T, Fiehn O (2016) SPLASH, a hashed identifier for mass spectra. Nat Biotechnol 34: 1099-101.
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2015

Shabuer G, Ishida K, Pidot SJ, Roth M, Dahse HM, Hertweck C (2015) Plant pathogenic anaerobic bacteria use aromatic polyketides to access aerobic territory. Science 350: 670-4.
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Santhanam R, Luu VT, Weinhold A, Goldberg J, Oh Y, Baldwin IT (2015) Native root-associated bacteria rescue a plant from a sudden-wilt disease that emerged during continuous cropping. PNAS 112: E5013-20
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Berry D, Mader E, Lee TK, Woebken D, Palatinszky M, Schmid MC, Hanson BT, Wang Y, Zhu D, Schintlmeister A, Wagner M, Shterzer N, Mizrahi I, Rauch I, Decker T, Bocklitz T, Popp J, Gibson CM, Fowler PW, Huang WE (2015) Tracking heavy water (D2O) incorporation for identifying and sorting active microbial cells. PNAS 112: E194-203.
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Lange M, Eisenhauer N, Sierra CA, Bessler H, Engels C, Griffiths RI, Mellado-Vázquez PG, Malik AA, Roy J, Scheu S, Steinbeiss S, Thomson BC, Trumbore SE, Gleixner (2015) Plant diversity increases soil microbial activity and soil carbon storage. Nat Commun 6: 6707.
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2014

Wicker K, Heintzmann R (2014) Resolving a misconception about structured illumination. Nat Photonics 8: 342-4.
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Bos KI, Harkins KM, Herbig A, Coscolla M, Weber N, Comas I, Forrest SA, Bryant JM, Harris SR, Schuenemann VJ, Campbell TJ, Majander K, Wilbur AK, Guichon RA, Wolfe Steadman DL, Cook DC, Niemann S, Behr MA, Zumarraga M, Bastida R, Huson D, Nieselt K, Young D, Parkhill J, Buikstra JE, Gagneux S, Stone AC, Krause J (2014) Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis. Nature 514: 494-7.
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Press AT, Traeger A, Pietsch C, Mosig A, Wagner M, Jbeily N, Koch N, Gottschaldt M, Ermolayev V, Beziere N, Popp J, Kessels M, Qualmann B, Clemens MG, Ntziachristos V, Schubert US, Bauer M (2014) Cell type-specific delivery of short interfering RNAs by dyefunctionalised theranostic nanoparticles. Nat Commun 5: 5565.
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Hädrich S, Klenke A, Rothhardt J, Krebs M, Hoffmann A, Pronin O, Pervak V, Limpert J, Tünnermann A (2014). High photon flux table-top coherent extreme-ultraviolet source. Nat Photonics 8: 779-83.

Warinner C, Rodrigues JFM, Vyas R, Trachsel C, Shved N, Grossmann J, Radini A, Hancock Y, Tito RY, Fiddyment S, Speller C, Hendy J, Charlton S, Luder HU, Salazar-García DC, Eppler E, Seiler R, Hansen L, Samaniego Castruita JA, Barkow-Oesterreicher S, Teoh KY, Kelstrup C, Olsen JV, Nanni P, Kawai T, Willerslev E, von Mering C, Lewis Jr. CM, Collins MJ, Gilbert MTP, Rühli F, Cappellini E (2014) Pathogens and host immunity in the ancient human oral cavity. Nat Genet 46: 336-44.
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2013

Bretschneider T, Heim JB, Heine D, Winkler R, Busch B, Kusebauch B, Stehle T, Zocher G, Hertweck C (2013) Vinylogous chain branching catalyzed by a dedicated polyketide synthase module. Nature 502: 124-8.
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Schuenemann VJ, Singh P, Mendum TA, Krause-Kyora B, Jäger G, Bos KI, Herbig A, Economou C, Benjak A, Busso P, Nebel A, Boldsen JL, Kjellström A, Wu H, Stewart GR, Taylor GM, Bauer P, Lee OY, Wu HH, Minnikin DE, Besra GS, Tucker K, Roffey S, Sow SO, Cole ST, Nieselt K, Krause J (2013) Genome-wide comparison of medieval and modern Mycobacterium leprae. Science 341: 179-83.
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Gröschel AH, Walther A, Löbling TI, Schacher FH, Schmalz H, Müller AHE (2013) Guided hierarchical co-assembly of soft patchy nanoparticles. Nature 503: 247-51.
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Wondraczek L, Batentschuk M, Schmidt MA, Borchardt R, Scheiner S, Seemann B, Schweizer P, Brabec CJ (2013) Solar spectral conversion for improving the photosynthetic activity in algae reactors. Nat Commun 4: 2047.
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2009

Aimanianda V, Bayry J, Bozza S, Kniemeyer O, Perruccio K, Ramulu Elluru S, Clavaud C, Paris S, Brakhage AA, Kaveri SV, Romani L, Latgé JP (2009) Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460: 1117-21.
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