Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease.
Nychas E, Marfil-Sánchez A, Chen X, Mirhakkak M, Li H, Jia W, Xu A, Nielsen HB, Nieuwdorp M, Loomba R, Ni Y, Panagiotou G 2025 Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease. Microbiome 13, 10.
Abstract
The pathogenesis of non-alcoholic fatty liver disease (NAFLD) with a global prevalence of 30% is multifactorial and the involvement of gut bacteria has been recently proposed. However, finding robust bacterial signatures of NAFLD has been a great challenge, mainly due to its co-occurrence with other metabolic diseases.